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| Registros recuperados: 100 | |
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| Oliveira,Monique Cristine de; Schoffen,João Paulo Ferreira. |
| Various theories try to explain the biological aging by changing the functions and structure of organic systems and cells. During lifetime, free radicals in the oxidative stress lead to lipid peroxidation of cellular membranes, homeostasis imbalance, chemical residues formation, gene mutations in DNA, dysfunction of certain organelles, and the arise of diseases due to cell death and/or injury. This review describes the action of oxidative stress in the cells aging process, emphasizing the factors such as cellular oxidative damage, its consequences and the main protective measures taken to prevent or delay this process. Tests with antioxidants: vitamins A, E and C, flavonoids, carotenoids and minerals, the practice of caloric restriction and physical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Cellular aging; Cell death; Oxidative stress. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600009 |
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| Chakraborty,Usha; Pradhan,Bhumika. |
| Five varieties of wheat (Triticum aestivum L.) - KW, UP 2752, PBW 343, SO and LV - were subjected to water stress and sampling was done on the 3rd, 6th and 9th day of stress. RWC decline in KW, UP 2752 and PBW 343 (36.65, 42.34 and 40.75% respectively) was comparatively lesser than in LV and SO (52.93 and 52.67% respectively). In all varieties tested, three antioxidant enzymes (POX, APOX and GR) showed an initial increase. The activity of POX and GR increased with the increase in the duration of stress in KW, UP 2752 and PBW 343, while the activity of APOX declined. However, CAT and SOD showed an initial increase in these varieties, whereas it declined in SO and LV with increase in the period of stress. Accumulation of H2O2 declined during prolonged water... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Carotenoids; Drought; Lipid peroxidation. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202012000200005 |
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| CHAMY,VERÓNICA M; LEPE,JAIME; CATALÁN,ÁLVARO; RETAMAL,DAVID; ESCOBAR,JORGE A; MADRID,EVA M. |
| Pre-eclampsia is a hypertensive disorder of pregnancy in which enzymatic antioxidant defenses fail and tissues are injured. This prospective case-control study evaluated whether pre-eclamptic women and their newborns show higher degrees of oxidative stress than normal pregnancies and sought to determine if this stress is related to clinical severity. Forty-four pre-eclamptic and thirty healthy pregnant women attending two hospitals in Valparaíso, Chile, were studied. The following plasmatic variables of antioxidant capacity were evaluated: glutathione peroxidase activity (GPx), total antioxidant capacity measured by oxidation of ABTS substrate (2,2'-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid), and superoxide dismutase activity (SOD). malondialdehide... |
| Tipo: Journal article |
Palavras-chave: Pre-eclampsia; MDA; SOD; GPx; ABTS; Lipoperoxidation; Antioxidants. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200005 |
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| Rosa,R.M.; Roesler,R.; Braga,A.L.; Saffi,J.; Henriques,J.A.P.. |
| The pharmacology of synthetic organoselenium compounds indicates that they can be used as antioxidants, enzyme inhibitors, neuroprotectors, anti-tumor and anti-infectious agents, and immunomodulators. In this review, we focus on the effects of diphenyl diselenide (DPDS) in various biological model organisms. DPDS possesses antioxidant activity, confirmed in several in vitro and in vivo systems, and thus has a protective effect against hepatic, renal and gastric injuries, in addition to its neuroprotective activity. The activity of the compound on the central nervous system has been studied since DPDS has lipophilic characteristics, increasing adenylyl cyclase activity and inhibiting glutamate and MK-801 binding to rat synaptic membranes. Systemic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diphenyl diselenide; Organoselenium; Antioxidants; Neuroprotection; Saccharomyces cerevisiae; Mutagenesis. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001000001 |
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| Bouriche,Hamama; Kada,Seoussen; Senator,Abderrahmane; demirtas,Ibrahim; Ozen,Tevfik; Toptanci,Bircan Çeken; Kizil,Goksel; Kizil,Murat. |
| ABSTRACT The protective activity of methanolic (Met E) and aqueous (Aq E) extracts of Globularia alypum L. (G. alypum) against DNA, lipid and protein oxidative damage was investigated. Moreover, the scavenging, chelating, and reducing power activities of the extracts were also evaluated. Phytochemical analysis was performed to determine phenolic compounds. Results showed that Met E and Aq E were rich in phenolic compounds, and were able to scavenge DPPH˙ with IC50 values of 48.61 µg/mL and 51.97 µg/mL, respectively. In addition, both extracts were able to chelate ferrous ions. At 300 μg/mL, the chelating activity was 97.53% and 91.02%, respectively. The reducing power of these extracts was also remarkable and concentration dependent. At 100 µg/mL, both... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; DNA damage; Globularia alypum; Lipid peroxidation; Protein oxidation. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100422 |
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| Sosa,P.M.; Schimidt,H.L.; Altermann,C.; Vieira,A.S.; Cibin,F.W.S.; Carpes,F.P.; Mello-Carpes,P.B.. |
| Stroke is the third most common cause of death worldwide, and most stroke survivors present some functional impairment. We assessed the striatal oxidative balance and motor alterations resulting from stroke in a rat model to investigate the neuroprotective role of physical exercise. Forty male Wistar rats were assigned to 4 groups: a) control, b) ischemia, c) physical exercise, and d) physical exercise and ischemia. Physical exercise was conducted using a treadmill for 8 weeks. Ischemia-reperfusion surgery involved transient bilateral occlusion of the common carotid arteries for 30 min. Neuromotor performance (open-field and rotarod performance tests) and pain sensitivity were evaluated beginning at 24 h after the surgery. Rats were euthanized and the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Stroke; Striatum; Locomotion; Oxidative stress; Antioxidants; Running. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000900798 |
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| Arshad,Wajeeha; Khan,Haji Muhammad Shoaib; Akhtar,Naveed; Mohammad,Imran Shair. |
| Currently, the use of natural compounds obtained from plants tremendously increased due to their promising therapeutic properties. The aim of this study was to formulate a stable emulgel formulation loaded with Cinnamomum tamala (CT) extract. The antioxidant activity of plant extract was determined by DPPH inhibition assay. The extract was successfully loaded into an emulgels using different concentrations of carbopol-940, liquid paraffin, emulsifying agents and preservatives. Preliminary stability study was performed of 17 CT emulgel formulations at accelerated temperature of 50 °C for 2-months. Organoleptic evaluation, centrifugation, globule size, pH, electrical conductivity and rheological studies were performed for a period of 90-days at different... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cinnamomum tomala; Antioxidants; Emulgel; Physicak stability; Non-Newtonian; Pseudo-plasticity. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100553 |
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| GALLEGO RÚA,Adriana María; HENAO RAMÍREZ,Ana María; URREA TRUJILLO,Aura Inés; ATEHORTÚA GARCÉS,Lucía. |
| In order to understand the causes of lack of regeneration in cacao somatic embryos, two cacao varieties with different responses to regeneration potential were described based on their capacity to store different compounds. It is well known that seed reserves play a central role in the regenerative capability of somatic embryos; thus, we followed histochemical changes and reserve fluctuations of proteins, polysaccharides and polyphenols during somatic embryogenesis (SE) in the two cacao varieties. The study showed that, in somatic embryos of the regenerating variety, polyphenols were localized mainly in the periphery of the embryo (epidermal cells) and proteins were the main storage substance in the embryo expression medium, while the non-regenerating... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Histology; Reserve accumulation; Recalcitrance; Somatic embryogenesis. |
| Ano: 2016 |
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2016000200002 |
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| Llanio, M. D.; Fernández, M. D.; Mata, A.; Cabrera, B.; Valdés-Iglesias, O.; Díaz, C.; Cabranes, Y.. |
| Marine organisms represent a new source for the discovery of anti-inflammatory agents (Grace et al., 1994), mainly obtained starting from sponges, coelenterates and algae. A representative compound from algae, due to its great number of properties, is the epitaondiol that inhibits the phospholipase A2 and the formation and/or release of prostaglandins and leukotrienes. Taking into account these antecedents, we decided to evaluate extracts from four Rhodophyte algae species of the genera Laurencia, Acantophora and Gracilaria in the models of mouse ear oedema induced by croton oil, writhing induced by acetic acid in mouse, and the assay of the tiobarbituric acid (TBA). The objective was to detect antiinflammatory, analgesic and antioxidant properties of the... |
| Tipo: Journal Contribution |
Palavras-chave: Algae; Antioxidants; Algae; Antioxidants; Http://aims.fao.org/aos/agrovoc/c_258; Http://aims.fao.org/aos/agrovoc/c_511. |
| Ano: 2003 |
URL: http://hdl.handle.net/1834/3343 |
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| PRADEEP,KANNAMPALLI; RAJ MOHAN,CHANDRASEKARAN VICTOR; GOBIANAND,KUPANNAN; KARTHIKEYAN,SIVANESAN. |
| Diethylnitrosamine (DEN), found in many commonly consumed foods, is widely reported to induce cancer in animals and humans. The aim of the present study was to investigate the hepatoprotective and antioxidant activities of the leaf extract of the medicinal plant Cassia fistula Linn. against diethylnitrosamine induced liver injury in ethanol pretreated rats. Albino Wistar rats, pretreated with ethanol for 15 days, were administered a single dose of DEN. Thirty days after DEN administration, hepatotocellular damage was observed histologically, along with elevated levels of serum AST, ALT, ALP, LDH, γ-GT and bilirubin and a simultaneous fall in the levels of the marker enzymes in the liver tissue. Liver oxidative stress was confirmed by elevated... |
| Tipo: Journal article |
Palavras-chave: Antioxidants; Cassia fistula; Diethylnitrosamine; Hepatoprotective; Lipid peroxidation; Silymarin. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000100013 |
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| MORENO,MARINES BATALHA; CANTILLANO,RUFINO FERNANDO FLORES; ROMBALDI,CESAR VALMOR; MANICA-BERTO,ROBERTA. |
| ABSTRACT The aim of this study was to evaluate the ability to prolong the useful life of the minimally processed ‘Fuji’ apple by applying the individual or combined additives (L-cysteine chloride, L-ascorbic acid and calcium chloride) and to determine the appropriate period of storage of the whole fruit to perform the minimum processing. The experimental design was completely randomized in three-factor design with three replications. Factor A was composed of storage periods of whole apples, pre-processing, in cold chambers (20, 78, 138 and 188 days); the factor B was represented by storage periods minimum post-processing, simulating shelf life (3, 6, 9 and 12 days), and factor C was represented by chemical additives (distilled water, as control, 0.5%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidants; Malus domestica; Storage; Minimally processing. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452016000400902 |
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| VEBER,BRUNO; CAMARGO,ANDERSON; DALMAGRO,ANA PAULA; BONDE,HENRIQUE LUIS P.; MAGRO,DÉBORA D. DAL; LIMA,DANIELA D. DE; ZENI,ANA LÚCIA B.. |
| Abstract Red cabbage (Brassica oleracea L. var. capitata f. rubra DC.) extract has been demonstrated hypolipidemic and antioxidant capacity. Herein, we investigated the effect of red cabbage aqueous extract (RC) or fenofibrate (FF) in oxidative stress induced by Triton WR-1339 in rats. The antioxidant capacity was evaluated through the superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities and, thiobarbituric reactive species (TBARS) and protein carbonyl (PC) levels in erythrocytes, liver, kidneys, cerebral cortex and hippocampus of male rats. The alterations promoted by Triton WR-1339 in enzymatic antioxidant defense in the liver, kidneys and hippocampus were reversed by RC or FF treatments. The TBARS and PC levels... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Red cabbage; Brassica oleracea; Oxidative stress; Antioxidants; Triton WR-1339. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100711 |
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| Vellosa,José Carlos Rebuglio; Khalil,Najeh Maissar; Gutierres,Vânia Ortega; Santos,Vânia Aparecida de Freitas Formenton Macedo dos; Furlan,Maysa; Brunetti,Iguatemy Lourenço; Oliveira,Olga Maria Mascarenhas de Faria. |
| Reactive oxygen species (ROS) and free radical species have been implicated in initiating or accompanying many diseases in living organisms; there is thus, a continual need for antioxidants molecules to inactivate ROS/free radicals. Many studies of plants crude extracts have demonstrated free-radical scavenging and antioxidant action. Salacia species have long been used, in several countries, as traditional medicines against certain diseases and for their anti-inflammatory properties. In this study, Salacia campestris Walp (Hippocrateaceae) root bark ethanol extract (ScEtOH) was assessed for its ability to scavenge free radicals and reactive oxygen species; the results were expressed as percentage inhibition of the active species. ScEtOH was efficient... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Salacia campestris Walp/antioxidant properties; Hippocrateaceae; Myeloperoxidase; Reactive oxygen species; Antioxidants; Free radicals. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000100012 |
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| Messina, Concetta Maria; Troia, Angelo; Arena, Rosaria; Manuguerra, Simona; Ioannou, Theodora; Curcuraci, Eleonora; Renda, Giuseppe; Hellio, Claire; Santulli, Andrea. |
| n this study we focused on four taxa of the genus Calendula (C. maritima, C. suffruticosa subsp. fulgida, C. arvensis, and the hybrid between the first two ones), collected in Mediterranean area (Sicily). Six extracts for each species were obtained using solvents with increasing polarity (hexane, ethanol 80%, acetone 70%, and water) and through extraction by supercritical fluids (SFE). It has been observed that the solvent with the highest extraction efficiency was ethanol 80% for all species. However, SFE extracts showed high antioxidant activity comparable to the ethanol 80% extract (polyphenol, DPPH, and reducing power method). These findings were confirmed by in vitro analysis (MTT assay) where it was observed that the tested concentration (24 µg/mL),... |
| Tipo: Text |
Palavras-chave: Calendula species; Marigold; Supercritical fluid extraction; Bioactivity; Antioxidants; Polyphenols. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00591/70336/68389.pdf |
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| Registros recuperados: 100 | |
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